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Integrin β4-targeted cancer immunotherapies inhibit tumor growth and decrease metastasis
Integrin β4 (ITGB4) has been shown to play an important role in the regulation of cancer stem cells (CSCs). Immune targeting of ITGB4 represents a novel approach to target this cell population with potential clinical benefit. We developed two immunologic strategies to target ITGB4: ITGB4 protein-pul...
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| Veröffentlicht in: | Cancer Res |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7024642/ https://ncbi.nlm.nih.gov/pubmed/31843981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-1145 |
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