Integrin β4-targeted cancer immunotherapies inhibit tumor growth and decrease metastasis

Integrin β4 (ITGB4) has been shown to play an important role in the regulation of cancer stem cells (CSCs). Immune targeting of ITGB4 represents a novel approach to target this cell population with potential clinical benefit. We developed two immunologic strategies to target ITGB4: ITGB4 protein-pul...

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Udgivet i:Cancer Res
Main Authors: Ruan, Shasha, Lin, Ming, Zhu, Yong, Lum, Lawrence G., Thakur, Archana, Jin, Runming, Shao, Wenlong, Zhang, Yalei, Hu, Yangyang, Huang, Shiang, Hurt, Elaine M., Chang, Alfred E., Wicha, Max S., Li, Qiao
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7024642/
https://ncbi.nlm.nih.gov/pubmed/31843981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-1145
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