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p53 Integrates Temporal WDR5 Inputs during Neuroectoderm and Mesoderm Differentiation of Mouse Embryonic Stem Cells

How ubiquitous transcription factors (TFs) coordinate temporal inputs from broadly expressed epigenetic factors to control cell fate remains poorly understood. Here, we uncover a molecular relationship between p53, an abundant embryonic TF, and WDR5, an essential member of the MLL chromatin modifyin...

詳細記述

保存先:
書誌詳細
出版年:Cell Rep
主要な著者: Li, Qiang, Mao, Fengbiao, Zhou, Bo, Huang, Yuanhao, Zou, Zhenhua, denDekker, Aaron D., Xu, Jing, Hou, Sean, Liu, Jie, Dou, Yali, Rao, Rajesh C.
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7024586/
https://ncbi.nlm.nih.gov/pubmed/31940490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.12.039
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