The p53 Family Coordinates Wnt and Nodal Inputs in Mesendodermal Differentiation of Embryonic Stem Cells

In this study we outline a regulatory network that involves the p53 tumor suppressor family and the Wnt pathway acting together with the TGF-β pathway in mesendodermal differentiation of mouse and human embryonic stem cells. Knockout of all three members, p53, p63 and p73, shows that the p53 family...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell Stem Cell
Päätekijät: Wang, Qiong, Zou, Yilong, Nowotschin, Sonja, Kim, Sang Yong, Li, Qing V., Soh, Chew-Li, Su, Jie, Zhang, Chao, Shu, Weiping, Xi, Qiaoran, Huangfu, Danwei, Hadjantonakis, Anna-Katerina, Massagué, Joan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5218926/
https://ncbi.nlm.nih.gov/pubmed/27889317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2016.10.002
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