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Allosteric Cannabinoid Receptor 1 (CB1) Ligands Reduce Ocular Pain and Inflammation

Cannabinoid receptor 1 (CB1) activation has been reported to reduce transient receptor potential cation channel subfamily V member 1 (TRPV1)-induced inflammatory responses and is anti-nociceptive and anti-inflammatory in corneal injury. We examined whether allosteric ligands, can modulate CB1 signal...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Thapa, Dinesh, Cairns, Elizabeth A., Szczesniak, Anna-Maria, Kulkarni, Pushkar M., Straiker, Alex J., Thakur, Ganesh A., Kelly, Melanie E. M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7024337/
https://ncbi.nlm.nih.gov/pubmed/31968549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25020417
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