Identification and Repurposing of Trisubstituted Harmine Derivatives as Novel Inhibitors of Mycobacterium tuberculosis Phosphoserine Phosphatase

Mycobacterium tuberculosis is still the deadliest bacterial pathogen worldwide and the increasing number of multidrug-resistant tuberculosis cases further complicates this global health issue. M. tuberculosis phosphoserine phosphatase SerB2 is a promising target for drug design. Besides being a key...

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Publicado en:Molecules
Autores principales: Pierson, Elise, Haufroid, Marie, Gosain, Tannu Priya, Chopra, Pankaj, Singh, Ramandeep, Wouters, Johan
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7024313/
https://ncbi.nlm.nih.gov/pubmed/31963843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25020415
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