Inorganic polyphosphate accumulation suppresses the dormancy response and virulence in Mycobacterium tuberculosis

Stringent response pathways involving inorganic polyphosphate (PolyP) play an essential role in bacterial stress adaptation and virulence. The intracellular levels of PolyP are modulated by the activities of polyphosphate kinase-1 (PPK1), polyphosphate kinase-2 (PPK2), and exopolyphosphatases (PPXs)...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Tiwari, Prabhakar, Gosain, Tannu Priya, Singh, Mamta, Sankhe, Gaurav D., Arora, Garima, Kidwai, Saqib, Agarwal, Sakshi, Chugh, Saurabh, Saini, Deepak K., Singh, Ramandeep
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6635458/
https://ncbi.nlm.nih.gov/pubmed/31113860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008370
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