Inorganic polyphosphate accumulation suppresses the dormancy response and virulence in Mycobacterium tuberculosis

Stringent response pathways involving inorganic polyphosphate (PolyP) play an essential role in bacterial stress adaptation and virulence. The intracellular levels of PolyP are modulated by the activities of polyphosphate kinase-1 (PPK1), polyphosphate kinase-2 (PPK2), and exopolyphosphatases (PPXs)...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Tiwari, Prabhakar, Gosain, Tannu Priya, Singh, Mamta, Sankhe, Gaurav D., Arora, Garima, Kidwai, Saqib, Agarwal, Sakshi, Chugh, Saurabh, Saini, Deepak K., Singh, Ramandeep
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2019
Matèries:
Microbiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6635458/
https://ncbi.nlm.nih.gov/pubmed/31113860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008370
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