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The Senescence-Associated Matricellular Protein CCN1 in Plasma of Human Subjects with Idiopathic Pulmonary Fibrosis

INTRODUCTION: Cellular senescence has been linked to the pathogenesis of idiopathic pulmonary fibrosis (IPF). CCN1 is a matricellular protein that has been shown to induce cellular senescence and contribute to lung fibrosis in pre-clinical models. In this report, we determined plasma CCN1 levels in...

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Detalhes bibliográficos
Publicado no:Respir Med
Main Authors: Kulkarni, Tejaswini, Kurundkar, Ashish R., Kim, Young-il, de Andrade, Joao, Luckhardt, Tracy, Thannickal, Victor J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7023981/
https://ncbi.nlm.nih.gov/pubmed/31765873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.rmed.2019.105821
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