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Natural genetic variation reveals key features of epigenetic and transcriptional memory in virus-specific CD8 T cells

Stable changes in chromatin states and gene expression in cells of the immune system form the basis for memory of infections and other challenges. Here, we used naturally occurring cis-regulatory variation in wild-derived inbred mouse strains to explore the mechanisms underlying long-lasting vs. tra...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Immunity
Egile Nagusiak: van der Veeken, Joris, Zhong, Yi, Sharma, Roshan, Mazutis, Linas, Dao, Phuong, Pe’er, Dana, Leslie, Christina S., Rudensky, Alexander Y.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7023907/
https://ncbi.nlm.nih.gov/pubmed/31027997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2019.03.031
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