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Actively Targeted and Redox Responsive Delivery of Anticancer Drug by Chitosan Nanoparticles
The clinical efficacy of methotrexate (MTX) is limited by its poor water solubility, its low bioavailability, and the development of resistance in cancer cells. Herein, we developed novel folate redox-responsive chitosan (FTC) nanoparticles for intracellular MTX delivery. l-Cysteine and folic acid m...
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| Veröffentlicht in: | Pharmaceutics |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7023447/ https://ncbi.nlm.nih.gov/pubmed/31888000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12010026 |
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