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Preparation and characterization of novel chitosan–protamine nanoparticles for nucleus-targeted anticancer drug delivery

It is well known that most anticancer drugs commonly show high toxicity to the DNA of tumor cells and exert effects by combining with the DNA or associated enzymes in the nucleus. Most developed drugs are first delivered into the cytoplasm and then transferred to the nucleus through the membrane por...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Yu, Xiwei, Hou, Jiahui, Shi, Yijie, Su, Chang, Zhao, Liang
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5115688/
https://ncbi.nlm.nih.gov/pubmed/27881917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S117066
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