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Preparation and characterization of novel chitosan–protamine nanoparticles for nucleus-targeted anticancer drug delivery

It is well known that most anticancer drugs commonly show high toxicity to the DNA of tumor cells and exert effects by combining with the DNA or associated enzymes in the nucleus. Most developed drugs are first delivered into the cytoplasm and then transferred to the nucleus through the membrane por...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Nanomedicine
Hauptverfasser: Yu, Xiwei, Hou, Jiahui, Shi, Yijie, Su, Chang, Zhao, Liang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5115688/
https://ncbi.nlm.nih.gov/pubmed/27881917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S117066
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