Intracellular targeted co-delivery of shMDR1 and gefitinib with chitosan nanoparticles for overcoming multidrug resistance

Nowadays, multidrug resistance and side effects of drugs limit the effectiveness of chemotherapies in clinics. P-glycoprotein (P-gp) (MDR1), as a member of the ATP-binding cassette family, acts on transporting drugs into cell plasma across the membrane of cancer cells and leads to the occurrence of...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Int J Nanomedicine
Main Authors: Yu, Xiwei, Yang, Guang, Shi, Yijie, Su, Chang, Liu, Ming, Feng, Bo, Zhao, Liang
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2015
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648604/
https://ncbi.nlm.nih.gov/pubmed/26648717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S92436
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