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Redox-responsive cisplatin nanogels for anticancer drug delivery

Inspired by cisplatin’s deactivation by glutathione (GSH) in cancer, a GSH responsive nanogel loaded with doxorubicin (Dox) was prepared using hyaluronan as a matrix and cisplatin as a crosslinker. The elevated GSH depletes the cisplatin crosslinker in the nanogel, enhances Dox release and boosts cy...

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書目詳細資料
發表在:Chem Commun (Camb)
Main Authors: Zhang, Weiqi, Tung, Ching-Hsuan
格式: Artigo
語言:Inglês
出版: 2018
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6057802/
https://ncbi.nlm.nih.gov/pubmed/29995047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8cc01795f
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