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Redox-responsive cisplatin nanogels for anticancer drug delivery
Inspired by cisplatin’s deactivation by glutathione (GSH) in cancer, a GSH responsive nanogel loaded with doxorubicin (Dox) was prepared using hyaluronan as a matrix and cisplatin as a crosslinker. The elevated GSH depletes the cisplatin crosslinker in the nanogel, enhances Dox release and boosts cy...
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| Publicado en: | Chem Commun (Camb) |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6057802/ https://ncbi.nlm.nih.gov/pubmed/29995047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8cc01795f |
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