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Melatonin Prevents Transforming Growth Factor-β1-Stimulated Transdifferentiation of Renal Interstitial Fibroblasts to Myofibroblasts by Suppressing Reactive Oxygen Species-Dependent Mechanisms

Accumulating evidence suggests that the pineal hormone melatonin displays protective effects against renal fibrosis, but the mechanisms remain poorly understood. Here, we investigate the effect of the pineal hormone on transdifferentiation of renal fibroblasts to myofibroblasts invoked by transformi...

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Dettagli Bibliografici
Pubblicato in:Antioxidants (Basel)
Autori principali: Kim, Jung-Yeon, Park, Jae-Hyung, Jeon, Eon Ju, Leem, Jaechan, Park, Kwan-Kyu
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7022732/
https://ncbi.nlm.nih.gov/pubmed/31906396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox9010039
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