Melatonin Prevents Transforming Growth Factor-β1-Stimulated Transdifferentiation of Renal Interstitial Fibroblasts to Myofibroblasts by Suppressing Reactive Oxygen Species-Dependent Mechanisms

Accumulating evidence suggests that the pineal hormone melatonin displays protective effects against renal fibrosis, but the mechanisms remain poorly understood. Here, we investigate the effect of the pineal hormone on transdifferentiation of renal fibroblasts to myofibroblasts invoked by transformi...

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Bibliografiske detaljer
Udgivet i:Antioxidants (Basel)
Main Authors: Kim, Jung-Yeon, Park, Jae-Hyung, Jeon, Eon Ju, Leem, Jaechan, Park, Kwan-Kyu
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7022732/
https://ncbi.nlm.nih.gov/pubmed/31906396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox9010039
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