Impact of Suboptimal APOBEC3G Neutralization on the Emergence of HIV Drug Resistance in Humanized Mice

HIV diversification facilitates immune escape and complicates antiretroviral therapy. In this study, we take advantage of a humanized-mouse model to probe the contribution of APOBEC3 mutagenesis to viral evolution. Humanized mice were infected with isogenic HIV molecular clones (HIV-WT, HIV-45G, and...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Hernandez, Matthew M., Fahrny, Audrey, Jayaprakash, Anitha, Gers-Huber, Gustavo, Dillon-White, Marsha, Audigé, Annette, Mulder, Lubbertus C. F., Sachidanandam, Ravi, Speck, Roberto F., Simon, Viviana
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2020
Matèries:
Genetic Diversity and Evolution
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7022346/
https://ncbi.nlm.nih.gov/pubmed/31801862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01543-19
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars