The IFNL4 Gene Is a Noncanonical Interferon Gene with a Unique but Evolutionarily Conserved Regulation

Interferon lambda 4 (IFN-λ4) is a recently identified enigmatic member of the interferon (IFN) lambda family. Genetic data suggest that the IFNL4 gene acts in a proviral and anti-inflammatory manner in patients. However, the protein is indistinguishable in vitro from the other members of the interfe...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Zhou, Hao, Møhlenberg, Michelle, Terczyńska-Dyla, Ewa, Winther, Kasper Grønbjerg, Hansen, Nanna Hougaard, Vad-Nielsen, Johan, Laloli, Laura, Dijkman, Ronald, Nielsen, Anders Lade, Gad, Hans Henrik, Hartmann, Rune
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7022339/
https://ncbi.nlm.nih.gov/pubmed/31776283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01535-19
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