Skeletal loading regulates breast cancer-associated osteolysis in a loading intensity-dependent fashion

Osteocytes are mechanosensitive bone cells, but little is known about their effects on tumor cells in response to mechanical stimulation. We treated breast cancer cells with osteocyte-derived conditioned medium (CM) and fluid flow-treated conditioned medium (FFCM) with 0.25 Pa and 1 Pa shear stress....

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Vydáno v:Bone Res
Hlavní autoři: Fan, Yao, Jalali, Aydin, Chen, Andy, Zhao, Xinyu, Liu, Shengzhi, Teli, Meghana, Guo, Yunxia, Li, Fangjia, Li, Junrui, Siegel, Amanda, Yang, Lianxiang, Liu, Jing, Na, Sungsoo, Agarwal, Mangilal, Robling, Alexander G., Nakshatri, Harikrishna, Li, Bai-Yan, Yokota, Hiroki
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7021802/
https://ncbi.nlm.nih.gov/pubmed/32128277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41413-020-0083-6
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