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Structure of the full‐length Serratia marcescens acetyltransferase AAC(3)‐Ia in complex with coenzyme A

Acyl‐coenzyme A‐dependent N‐acetyltransferases (AACs) catalyze the modification of aminoglycosides rendering the bacteria carrying such enzymes resistant to this class of antibiotics. Here we present the crystal structure of AAC(3)‐Ia enzyme from Serratia marcescens in complex with coenzyme A determ...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Popov, Georgy, Evdokimova, Elena, Stogios, Peter J., Savchenko, Alexei
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7020991/
https://ncbi.nlm.nih.gov/pubmed/31876342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3811
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