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ApmA Is a Unique Aminoglycoside Antibiotic Acetyltransferase That Inactivates Apramycin

Apramycin is an aminoglycoside antibiotic with the potential to be developed to combat multidrug-resistant pathogens. Its unique structure evades the clinically widespread mechanisms of aminoglycoside resistance that currently compromise the efficacy of other members in this drug class. Of the amino...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Bordeleau, Emily, Stogios, Peter J., Evdokimova, Elena, Koteva, Kalinka, Savchenko, Alexei, Wright, Gerard D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7885111/
https://ncbi.nlm.nih.gov/pubmed/33563840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02705-20
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