TREX1 531C>T Polymorphism is Associated with High Proviral Load Levels in HTLV-1-Infected Persons

Human T-lymphotropic virus type 1 (HTLV-1) deregulates the immune system and cell cycle, resulting in loss of immune tolerance and disease, including HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Three prime repair exonuclease 1 (TREX1) maintains innate immune tolerance of the...

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Veröffentlicht in:Viruses
Hauptverfasser: Silva, Denis de Castro, Amoras, Ednelza da Silva Graça, Moura, Tuane Carolina Ferreira, Lopes, Felipe Teixeira, Gomes, Samara Tatielle Monteiro, da Costa, Carlos A., Sousa, Maísa Silva, Ishak, Ricardo, Vallinoto, Antonio Carlos Rosário, Queiroz, Maria Alice Freitas
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7019804/
https://ncbi.nlm.nih.gov/pubmed/31861565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12010007
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