The SAMHD1 rs6029941 (A/G) Polymorphism Seems to Influence the HTLV-1 Proviral Load and IFN-Alpha Levels

SAMHD1, a host dNTPase, acts as a retroviral restriction factor by degrading the pool of nucleotides available for the initial reverse transcription of retroviruses, including HTLV-1. Polymorphisms in the SAMDH1 gene may alter the enzymatic expression and influence the course of infection by the vir...

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Bibliografische gegevens
Gepubliceerd in:Front Cell Infect Microbiol
Hoofdauteurs: Queiroz, Maria Alice Freitas, Amoras, Ednelza da Silva Graça, Moura, Tuane Carolina Ferreira, da Costa, Carlos Araújo, de Sousa, Maisa Silva, Lima, Sandra Souza, Ishak, Ricardo, Vallinoto, Antonio Carlos Rosário
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2020
Onderwerpen:
Cellular and Infection Microbiology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7326033/
https://ncbi.nlm.nih.gov/pubmed/32656092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2020.00246
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