IKKε phosphorylates kindlin-2 to induce invadopodia formation and promote colorectal cancer metastasis

Invadopodia formation is a key driver of cancer metastasis. The noncanonical IkB-related kinase IKKε has been implicated in cancer metastasis, but its roles in invadopodia formation and colorectal cancer (CRC) metastasis are unclear. Methods: Immunofluorescence, gelatin-degradation assay, wound heal...

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Dettagli Bibliografici
Pubblicato in:Theranostics
Autori principali: Liu, Ge, Bao, Yantao, Liu, Chaohua, Zhu, Qinchang, Zhao, Lin, Lu, Xiaopeng, Zhu, Qian, Lv, Yafei, Bai, Feng, Wen, He, Sun, Yujie, Zhu, Wei-Guo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2020
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7019159/
https://ncbi.nlm.nih.gov/pubmed/32104508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.40397
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