Homo- and Heteroassociations Drive Activation of ErbB3

Dimerization or the formation of higher-order oligomers is required for the activation of ErbB receptor tyrosine kinases. The heregulin (HRG) receptor, ErbB3, must heterodimerize with other members of the family, preferentially ErbB2, to form a functional signal transducing complex. Here, we applied...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Váradi, Tímea, Schneider, Magdalena, Sevcsik, Eva, Kiesenhofer, Dominik, Baumgart, Florian, Batta, Gyula, Kovács, Tamás, Platzer, René, Huppa, Johannes B., Szöllősi, János, Schütz, Gerhard J., Brameshuber, Mario, Nagy, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2019
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7018998/
https://ncbi.nlm.nih.gov/pubmed/31653451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.10.001
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