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Quantitative Characterization of the Large-Scale Association of ErbB1 and ErbB2 by Flow Cytometric Homo-FRET Measurements

The association of receptor tyrosine kinases is a key step in the initiation of growth factor-mediated signaling. Although the ligand-induced dimerization of inactive, monomeric receptors was the central dogma of receptor tyrosine kinase activation for decades, the existence of larger oligomers is n...

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Hlavní autoři: Szabó, Ágnes, Horváth, Gábor, Szöllősi, János, Nagy, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483738/
https://ncbi.nlm.nih.gov/pubmed/18487307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.133371
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