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DNGR-1, a Dendritic Cell-Specific Sensor of Tissue Damage That Dually Modulates Immunity and Inflammation

DNGR-1 (encoded by CLEC9A) is a C-type lectin receptor (CLR) with an expression profile that is mainly restricted to type 1 conventional dendritic cells (cDC1s) both in mice and humans. This delimited expression pattern makes it appropriate for defining a cDC1 signature and for therapeutic targeting...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Cueto, Francisco J., del Fresno, Carlos, Sancho, David
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7018937/
https://ncbi.nlm.nih.gov/pubmed/32117205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.03146
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