Optimal generation of tissue-resident but not circulating memory T cells during viral infection requires crosspriming by DNGR-1(+) dendritic cells

Despite the crucial role of tissue-resident memory T (Trm) cells in protective immunity, their priming remains poorly understood. Here, we have shown differential priming requirements for Trm versus circulating memory CD8(+) T cells. In vaccinia cutaneous-infected mice, DNGR-1-mediated crosspresenta...

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Gepubliceerd in:Immunity
Hoofdauteurs: Iborra, Salvador, Martínez-López, María, Khouili, Sofía C., Enamorado, Michel, Cueto, Francisco J., Conde-Garrosa, Ruth, del Fresno, Carlos, Sancho, David
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5074364/
https://ncbi.nlm.nih.gov/pubmed/27692611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2016.08.019
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