Novel Cassette Assay To Quantify the Outer Membrane Permeability of Five β-Lactams Simultaneously in Carbapenem-Resistant Klebsiella pneumoniae and Enterobacter cloacae

Poor penetration through the outer membrane (OM) of Gram-negative bacteria is a major barrier of antibiotic development. While β-lactam antibiotics are commonly used against Klebsiella pneumoniae and Enterobacter cloacae, there are limited data on OM permeability especially in K. pneumoniae. Here, w...

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Publicat a:mBio
Autors principals: Kim, Tae Hwan, Tao, Xun, Moya, Bartolome, Jiao, Yuanyuan, Basso, Kari B., Zhou, Jieqiang, Lang, Yinzhi, Sutaria, Dhruvitkumar S., Zavascki, Alexandre P., Barth, Afonso L., Reeve, Stephanie M., Schweizer, Herbert P., Deveson Lucas, Deanna, Boyce, John D., Bonomo, Robert A., Lee, Richard E., Shin, Beom Soo, Louie, Arnold, Drusano, George L., Bulitta, Jürgen B.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7018653/
https://ncbi.nlm.nih.gov/pubmed/32047131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.03189-19
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