Comparable Efficacy and Better Safety of Double β-Lactam Combination Therapy versus β‑Lactam plus Aminoglycoside in Gram-Negative Bacteria in Randomized, Controlled Trials

There is a great need for efficacious therapies against Gram-negative bacteria. Double β-lactam combination(s) (DBL) are relatively safe, and preclinical data are promising; however, their clinical role has not been well defined. We conducted a metaanalysis of the clinical and microbiological effica...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Jiao, Yuanyuan, Moya, Bartolome, Chen, Mong-Jen, Zavascki, Alexandre P., Tsai, Hsinyin, Tao, Xun, Sutaria, Dhruvitkumar S., Louie, Arnold, Boyce, John D., Deveson Lucas, Deanna, Kim, Tae Hwan, Tsuji, Brian T., Bonomo, Robert A., Drusano, George L., Bulitta, Jürgen B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591590/
https://ncbi.nlm.nih.gov/pubmed/30988147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00425-19
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