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Aging aggravates intervertebral disc degeneration by regulating transcription factors toward chondrogenesis
Osterix is a critical transcription factor of mesenchymal stem cell fate, where its loss or loss of WNT signaling diverts differentiation to a chondrocytic lineage. Intervertebral disc (IVD) degeneration activates differentiation of prehypertrophic chondrocyte-like cells and inactivates WNT signalin...
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| Yayımlandı: | FASEB J |
|---|---|
| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2019
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7018543/ https://ncbi.nlm.nih.gov/pubmed/31909538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201902109R |
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