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Maximum Reproductive Lifespan Correlates with CD33rSIGLEC Gene Number: Implications for NADPH Oxidase-derived Reactive Oxygen Species in Aging

Humans and orcas are among the very rare species that have a prolonged post-reproductive lifespan (PRLS), during which the aging process continues. Reactive oxygen species (ROS) derived from mitochondria and from the NADPH-oxidase (NOX) enzymes of innate immune cells are known to contribute to aging...

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Bibliografiske detaljer
Udgivet i:FASEB J
Main Authors: Khan, Naazneen, Kim, Stuart K., Gagneux, Pascal, Dugan, Laura, Varki, Ajit
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7018541/
https://ncbi.nlm.nih.gov/pubmed/31907986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201902116R
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