Siglec receptors impact mammalian lifespan by modulating oxidative stress

Aging is a multifactorial process that includes the lifelong accumulation of molecular damage, leading to age-related frailty, disability and disease, and eventually death. In this study, we report evidence of a significant correlation between the number of genes encoding the immunomodulatory CD33-r...

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發表在:eLife
Main Authors: Schwarz, Flavio, Pearce, Oliver MT, Wang, Xiaoxia, Samraj, Annie N, Läubli, Heinz, Garcia, Javier O, Lin, Hongqiao, Fu, Xiaoming, Garcia-Bingman, Andrea, Secrest, Patrick, Romanoski, Casey E, Heyser, Charles, Glass, Christopher K, Hazen, Stanley L, Varki, Nissi, Varki, Ajit, Gagneux, Pascal
格式: Artigo
語言:Inglês
出版: eLife Sciences Publications, Ltd 2015
主題:
Genomics and Evolutionary Biology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384638/
https://ncbi.nlm.nih.gov/pubmed/25846707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.06184
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