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Interaction of yeast Rad51 and Rad52 relieves Rad52-mediated inhibition of de novo telomere addition

DNA double-strand breaks (DSBs) are toxic forms of DNA damage that must be repaired to maintain genome integrity. Telomerase can act upon a DSB to create a de novo telomere, a process that interferes with normal repair and creates terminal deletions. We previously identified sequences in Saccharomyc...

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Détails bibliographiques
Publié dans:PLoS Genet
Auteurs principaux: Epum, Esther A., Mohan, Michael J., Ruppe, Nicholas P., Friedman, Katherine L.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7018233/
https://ncbi.nlm.nih.gov/pubmed/32012161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008608
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