Endogenous Hot Spots of De Novo Telomere Addition in the Yeast Genome Contain Proximal Enhancers That Bind Cdc13

DNA double-strand breaks (DSBs) pose a threat to genome stability and are repaired through multiple mechanisms. Rarely, telomerase, the enzyme that maintains telomeres, acts upon a DSB in a mutagenic process termed telomere healing. The probability of telomere addition is increased at specific genom...

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Publicado en:Mol Cell Biol
Autores principales: Obodo, Udochukwu C., Epum, Esther A., Platts, Margaret H., Seloff, Jacob, Dahlson, Nicole A., Velkovsky, Stoycho M., Paul, Shira R., Friedman, Katherine L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2016
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907100/
https://ncbi.nlm.nih.gov/pubmed/27044869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00095-16
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