Dual CXCR4 and E-Selectin Inhibitor, GMI-1359, Shows Anti-Bone Metastatic Effects and Synergizes with Docetaxel in Prostate Cancer Cell Intraosseous Growth

Metastatic castration resistant prostate cancer (mCRPC) relapses due to acquired resistance to docetaxel-based chemotherapy and remains a major threat to patient survival. In this report, we tested the effectiveness of a dual CXCR4/E-selectin antagonist, GM-I1359, in vitro and in vivo, as a single a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cells
Main Authors: Festuccia, Claudio, Mancini, Andrea, Gravina, Giovanni Luca, Colapietro, Alessandro, Vetuschi, Antonella, Pompili, Simona, Ventura, Luca, Delle Monache, Simona, Iorio, Roberto, Del Fattore, Andrea, Fogler, William, Magnani, John
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017374/
https://ncbi.nlm.nih.gov/pubmed/31877673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9010032
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados