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The EGFR-TMEM167A-p53 Axis Defines the Aggressiveness of Gliomas
Despite the high frequency of EGFR and TP53 genetic alterations in gliomas, little is known about their crosstalk during tumor progression. Here, we described a mutually exclusive distribution between mutations in these two genes. We found that wild-type p53 gliomas are more aggressive than their mu...
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| Publié dans: | Cancers (Basel) |
|---|---|
| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MDPI
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7017250/ https://ncbi.nlm.nih.gov/pubmed/31947645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12010208 |
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