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The EGFR-TMEM167A-p53 Axis Defines the Aggressiveness of Gliomas

Despite the high frequency of EGFR and TP53 genetic alterations in gliomas, little is known about their crosstalk during tumor progression. Here, we described a mutually exclusive distribution between mutations in these two genes. We found that wild-type p53 gliomas are more aggressive than their mu...

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Bibliografski detalji
Izdano u:Cancers (Basel)
Glavni autori: Segura-Collar, Berta, Gargini, Ricardo, Tovar-Ambel, Elena, Hernández-SanMiguel, Esther, Epifano, Carolina, Pérez de Castro, Ignacio, Hernández-Laín, Aurelio, Casas-Tintó, Sergio, Sánchez-Gómez, Pilar
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017250/
https://ncbi.nlm.nih.gov/pubmed/31947645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12010208
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