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CD163(+) tumor‐associated macrophage accumulation in breast cancer patients reflects both local differentiation signals and systemic skewing of monocytes

OBJECTIVES: The accumulation of tumor‐associated macrophages (TAMs) is correlated with poor clinical outcome, but the mechanisms governing their differentiation from circulating monocytes remain unclear in humans. METHODS: Using multicolor flow cytometry, we evaluated TAMs phenotype in 93 breast can...

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Detalhes bibliográficos
Publicado no:Clin Transl Immunology
Main Authors: Ramos, Rodrigo Nalio, Rodriguez, Céline, Hubert, Margaux, Ardin, Maude, Treilleux, Isabelle, Ries, Carola H, Lavergne, Emilie, Chabaud, Sylvie, Colombe, Amélie, Trédan, Olivier, Guedes, Henrique Gomes, Laginha, Fábio, Richer, Wilfrid, Piaggio, Eliane, Barbuto, José Alexandre M, Caux, Christophe, Ménétrier‐Caux, Christine, Bendriss‐Vermare, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017151/
https://ncbi.nlm.nih.gov/pubmed/32082570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1108
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