Phosphoenolpyruvate from Glycolysis and PEPCK Regulate Cancer Cell Fate by Altering Cytosolic Ca(2+)

Changes in phosphoenolpyruvate (PEP) concentrations secondary to variations in glucose availability can regulate calcium signaling in T cells as this metabolite potently inhibits the sarcoplasmic reticulum Ca(2+)/ATPase pump (SERCA). This regulation is critical to assert immune activation in the tum...

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Bibliografische gegevens
Gepubliceerd in:Cells
Hoofdauteurs: Moreno-Felici, Juan, Hyroššová, Petra, Aragó, Marc, Rodríguez-Arévalo, Sergio, García-Rovés, Pablo M., Escolano, Carmen, Perales, Jose C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017135/
https://ncbi.nlm.nih.gov/pubmed/31861674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9010018
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