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Computational Analysis of Crystallization Additives for the Identification of New Allosteric Sites

[Image: see text] Allosteric effect can modulate the biological activity of a protein. Thus, the discovery of new allosteric sites is very attractive for designing new modulators or inhibitors. Here, we propose an innovative way to identify allosteric sites, based on crystallization additives (CA),...

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Publicat a:ACS Omega
Autors principals: Fogha, Jade, Diharce, Julien, Obled, Alan, Aci-Sèche, Samia, Bonnet, Pascal
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2020
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016913/
https://ncbi.nlm.nih.gov/pubmed/32064372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b02697
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