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Inhibition of Transcription Induces Phosphorylation of YB-1 at Ser102 and Its Accumulation in the Nucleus

The Y-box binding protein 1 (YB-1) is an RNA/DNA-binding protein regulating gene expression in the cytoplasm and the nucleus. Although mostly cytoplasmic, YB-1 accumulates in the nucleus under stress conditions. Its nuclear localization is associated with aggressiveness and multidrug resistance of c...

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Vydáno v:Cells
Hlavní autoři: Kretov, Dmitry A., Mordovkina, Daria A., Eliseeva, Irina A., Lyabin, Dmitry N., Polyakov, Dmitry N., Joshi, Vandana, Desforges, Bénédicte, Hamon, Loic, Lavrik, Olga I., Pastré, David, Curmi, Patrick A., Ovchinnikov, Lev P.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016903/
https://ncbi.nlm.nih.gov/pubmed/31906126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9010104
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