Inhibition of Transcription Induces Phosphorylation of YB-1 at Ser102 and Its Accumulation in the Nucleus

The Y-box binding protein 1 (YB-1) is an RNA/DNA-binding protein regulating gene expression in the cytoplasm and the nucleus. Although mostly cytoplasmic, YB-1 accumulates in the nucleus under stress conditions. Its nuclear localization is associated with aggressiveness and multidrug resistance of c...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Kretov, Dmitry A., Mordovkina, Daria A., Eliseeva, Irina A., Lyabin, Dmitry N., Polyakov, Dmitry N., Joshi, Vandana, Desforges, Bénédicte, Hamon, Loic, Lavrik, Olga I., Pastré, David, Curmi, Patrick A., Ovchinnikov, Lev P.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016903/
https://ncbi.nlm.nih.gov/pubmed/31906126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9010104
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