Inhibition of Transcription Induces Phosphorylation of YB-1 at Ser102 and Its Accumulation in the Nucleus

The Y-box binding protein 1 (YB-1) is an RNA/DNA-binding protein regulating gene expression in the cytoplasm and the nucleus. Although mostly cytoplasmic, YB-1 accumulates in the nucleus under stress conditions. Its nuclear localization is associated with aggressiveness and multidrug resistance of c...

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Publié dans:Cells
Auteurs principaux: Kretov, Dmitry A., Mordovkina, Daria A., Eliseeva, Irina A., Lyabin, Dmitry N., Polyakov, Dmitry N., Joshi, Vandana, Desforges, Bénédicte, Hamon, Loic, Lavrik, Olga I., Pastré, David, Curmi, Patrick A., Ovchinnikov, Lev P.
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016903/
https://ncbi.nlm.nih.gov/pubmed/31906126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9010104
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