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The Expanding Therapeutic Potential of Neuronal KCC2
Dysfunctions in GABAergic inhibitory neural transmission occur in neuronal injuries and neurological disorders. The potassium–chloride cotransporter 2 (KCC2, SLC12A5) is a key modulator of inhibitory GABAergic inputs in healthy adult neurons, as its chloride (Cl(−)) extruding activity underlies the...
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| Publié dans: | Cells |
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| Auteur principal: | |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MDPI
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7016893/ https://ncbi.nlm.nih.gov/pubmed/31963584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9010240 |
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