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The Therapeutic Potential of Neuronal K-Cl Co-Transporter KCC2 in Huntington’s Disease and Its Comorbidities
Intracellular chloride levels in the brain are regulated primarily through the opposing effects of two cation-chloride co-transporters (CCCs), namely K(+)-Cl(−) co-transporter-2 (KCC2) and Na(+)-K(+)-Cl(−) co-transporter-1 (NKCC1). These CCCs are differentially expressed throughout the course of dev...
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| Publicado no: | Int J Mol Sci |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7730145/ https://ncbi.nlm.nih.gov/pubmed/33266310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21239142 |
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