Cyclophilin A/EMMPRIN Axis Is Involved in Pro-Fibrotic Processes Associated with Thoracic Aortic Aneurysm of Marfan Syndrome Patients

Background: Marfan syndrome (MFS) is a genetic disease, characterized by thoracic aortic aneurysm (TAA), which treatment is to date purely surgical. Understanding of novel molecular targets is mandatory to unveil effective pharmacological approaches. Cyclophilin A (CyPA) and its receptor EMMPRIN are...

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Veröffentlicht in:Cells
Hauptverfasser: Perrucci, Gianluca L., Rurali, Erica, Corlianò, Maria, Balzo, Maria, Piccoli, Michela, Moschetta, Donato, Pini, Alessandro, Gaetano, Raffaella, Antona, Carlo, Egea, Gustavo, Fischer, Gunter, Malešević, Miroslav, Alamanni, Francesco, Cogliati, Elisa, Paolin, Adolfo, Pompilio, Giulio, Nigro, Patrizia
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016677/
https://ncbi.nlm.nih.gov/pubmed/31936351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9010154
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