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Cyclophilin A/EMMPRIN Axis Is Involved in Pro-Fibrotic Processes Associated with Thoracic Aortic Aneurysm of Marfan Syndrome Patients

Background: Marfan syndrome (MFS) is a genetic disease, characterized by thoracic aortic aneurysm (TAA), which treatment is to date purely surgical. Understanding of novel molecular targets is mandatory to unveil effective pharmacological approaches. Cyclophilin A (CyPA) and its receptor EMMPRIN are...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Perrucci, Gianluca L., Rurali, Erica, Corlianò, Maria, Balzo, Maria, Piccoli, Michela, Moschetta, Donato, Pini, Alessandro, Gaetano, Raffaella, Antona, Carlo, Egea, Gustavo, Fischer, Gunter, Malešević, Miroslav, Alamanni, Francesco, Cogliati, Elisa, Paolin, Adolfo, Pompilio, Giulio, Nigro, Patrizia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016677/
https://ncbi.nlm.nih.gov/pubmed/31936351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9010154
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